2013 ICRA Grantees
Genome Editing of the GWAS-Marked BCL11A Enhancer: An Approach to HbF Reactivation in Sickle Cell Disease
Daniel E. Bauer, M.D., Ph.D. and Stuart H Orkin, M.D.
Children’s Hospital, Boston and Harvard Medical School
Examination of Human Samples with Somatic Mutations in Hematopoietic Stem Cells to Inform the Biology of Fetal Hemoglobin Induction
Benjamin L. Ebert, M.D., Ph.D. and Maureen M. Okam, M.D., M.P.H.
Brigham and Women's Hospital and Harvard Medical School
"SCD Biochip": Towards a Simple and Reliable Way to Monitor Sickle Cell Disease
Umut A. Gurkan, Ph.D. and Jane A. Little, M.D.
Case Western Reserve University
Feasibility and Efficacy of a Home-Based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease
Steven J. Hardy, Ph.D. and Kristina K. Hardy, Ph.D.
Children’s National Medical Center
Novel Use Of Hydroxyurea in an African Region with Malaria
Chandy C. John, M.D.
University of Minnesota
The Effects of Hypoxia on Red Blood Cell-Dependent Thrombin Generation in Sickle
Nigel S. Key, MB ChB and Kenneth Mann, M.D.
University of North Carolina at Chapel Hill and University of Vermont
Gene Therapy for Sickle Cell Anemia
Punam Malik, M.D.
Cincinnati Children's Hospital Medical Center
Targeting Neutrophil Extracellular Traps in Sickle Cell Disease
Leslie V. Parise, Ph.D. and Bruce A. Sullenger, Ph.D.
University of North Carolina at Chapel Hill and Duke University Medical Center
Accurate and Inexpensive Point-of-Care Diagnosis of Sickle Cell Anemia
Rebecca R. Richards-Kortum, Ph.D.
William Marsh Rice University
Risk Stratification for Clinical Severity of Sickle Cell Disease in Nigeria and Assessment of Efficacy and Safety during Treatment with Hydroxyurea
Bamidele Tayo, Ph.D. and Victor R. Gordeuk, M.D.
Loyola University of Chicago and University of Illinois at Chicago