2013 ICRA Grantees

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2013 ICRA Grantees

Genome Editing of the GWAS-Marked BCL11A Enhancer: An Approach to HbF Reactivation in Sickle Cell Disease
Daniel E. Bauer, M.D., Ph.D. and Stuart H Orkin, M.D. 
Children’s Hospital, Boston and Harvard Medical School

Examination of Human Samples with Somatic Mutations in Hematopoietic Stem Cells to Inform the Biology of Fetal Hemoglobin Induction
Benjamin L. Ebert, M.D., Ph.D. and Maureen M. Okam, M.D., M.P.H. 
Brigham and Women's Hospital and Harvard Medical School

"SCD Biochip": Towards a Simple and Reliable Way to Monitor Sickle Cell Disease
Umut A. Gurkan, Ph.D. and Jane A. Little, M.D.
Case Western Reserve University

Feasibility and Efficacy of a Home-Based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease
Steven J. Hardy, Ph.D. and Kristina K. Hardy, Ph.D. 
Children’s National Medical Center

Novel Use Of Hydroxyurea in an African Region with Malaria
Chandy C. John, M.D. 
University of Minnesota

The Effects of Hypoxia on Red Blood Cell-Dependent Thrombin Generation in Sickle
Cell Disease

Nigel S. Key, MB ChB and Kenneth Mann, M.D. 
University of North Carolina at Chapel Hill and University of Vermont 

Site-Specific Gene Modification in Hematopoietic Stem Cells for Sickle Cell Disease
Donald Kohn, M.D.
University of California, Los Angeles

Gene Therapy for Sickle Cell Anemia
Punam Malik, M.D.
Cincinnati Children's Hospital Medical Center

Targeting Neutrophil Extracellular Traps in Sickle Cell Disease
Leslie V. Parise, Ph.D. and Bruce A. Sullenger, Ph.D. 
University of North Carolina at Chapel Hill and Duke University Medical Center

Accurate and Inexpensive Point-of-Care Diagnosis of Sickle Cell Anemia
Rebecca R. Richards-Kortum, Ph.D. 
William Marsh Rice University      

Risk Stratification for Clinical Severity of Sickle Cell Disease in Nigeria and Assessment of Efficacy and Safety during Treatment with Hydroxyurea
Bamidele Tayo, Ph.D. and Victor R. Gordeuk, M.D.
Loyola University of Chicago and University of Illinois at Chicago