Medical Research

2011 ICRA Grantees

Molecular Identification and Inhibition of the Deoxygenation-Activated, Calcium-Permeable Cation Channel of The Sickle Erythrocyte, Psickle, a Novel Therapeutic Target for Treatment of Sickle Disease

  • Seth L. Alper, M.D., Ph.D.
    Beth Israel Deaconess Medical Center

NRF2 Induction as Novel Treatment for Sickle Cell Disease

  • Jen-Tsan A. Chi, M.D., Ph.D. & Marilyn J. Telen, M.D.
    Duke University

Genomic Approaches to Prevent Red Blood Cell Alloimmunization in Patients with Sickle Cell Disease

  • Stella T. Chou, M.D. & Connie M. Westhoff, Ph.D.
    Children's Hospital of Philadelphia/New York Blood Center

Modeling Sickle Cell Anemia with Induced Pluripotent Stem Cells

  • George Q. Daley, M.D., Ph.D.
    Children's Hospital Boston

Effects of the Adenosine 2A Receptor Agonist Regadenoson on Sickle Cell Vaso-occlusion and Inflammation

  • Joshua J. Field, M.D., M.S. & Jonathan Lindner, M.D.
    The Medical College Of Wisconsin, Inc/ Oregon Health Sciences University

Nanoparticle-Mediated Correction of the Sickle Cell Disease Mutation

  • Peter M. Glazer, M.D., Ph.D.
    Yale University

Reversal of Sickle Cell-Related Chronic Kidney Disease

  • Antonio Guasch, M.D. & Marianne E.M. Yee, M.D., M.Sc.
    Emory University

Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease

  • Carolyn C. Hoppe, M.D., M.P.H.
    Children's Hospital and Research Center Oakland

Preclinical Evaluation of Globin Gene Transfer in Mobilized SCD Patient CD34+ Cells

  • Michel Sadelain, M.D., Ph.D. & Patricia A. Shi, M.D., MS
    Memorial Sloan-Kettering Cancer Center/New York Blood Center